Molecular jackhammers: a breakthrough in cancer treatment

An innovative technology uses vibrating molecules activated by infrared light to eliminate up to 99% of cancer cells in the laboratory.

A major breakthrough in photomedicine

Researchers in Texas have demonstrated that certain molecules, known as aminocyanines, can be activated by infrared light to vibrate at very high frequencies. These mechanical vibrations, known as Directed Vibronic Action, rupture the cell membranes of tumors without the use of heat or conventional chemical reactions.

Preclinical results by the numbers

• 99% of cancer cells destroyed in culture
• 50% complete remission in mice
• 10 cm of tissue penetration (NIR light)
• Vibrations at 40 trillion cycles per second

These results far exceed those of current treatments.

A unique mechanism of action

Unlike chemotherapy, this approach does not rely on toxic substances but on a physical effect. It works even at low temperatures (2 °C) and does not depend on the presenceof oxygen or free radicals.

A revolution in photobiomodulation?

These molecular jackhammers introduce a new light therapy modality that complements photobiomodulation. PBM could be used before or after treatment to stimulate cell regeneration or optimize the immune response.

Good to know : This approach could soon be incorporated into professional LED devices used in oncology.

Frequently Asked Questions

What is a molecular jackhammer?

It is a molecule activated by infrared light that vibrates at a high frequency and physically destroys cancer cells.

Is this technique available?

Not yet. Human clinical trials are expected to begin in 5 to 7 years.

Is this a form of photobiomodulation?

No, it's a new method based on a mechanical action, but it complements traditional PBM.

Scientific sources cited

• Molecular jackhammers eradicate cancer cells through vibronic-driven action
  James Tour, Ciceron Ayala-Orozco et al.
  Nature Chemistry, 2023
  https://www.nature.com/articles/s41557-023-01383-y
  Explains the mechanism of molecular vibrations activated by near-infrared light.
• Molecular jackhammers: Good vibrations eradicate cancer cells
  Science Alert, 2023
  https://www.sciencealert.com/scientists-destroy-99-of-cancer-cells-in-the-lab-using-vibrating-molecules
  A layman’s summary of the preclinical results, with key figures.
• PubMed - Vibronic-driven action and cancer remission in mice
  PubMed ID: 38114816
  https://pubmed.ncbi.nlm.nih.gov/38114816/
  Confirms the remission observed in mouse models of melanoma.

See also

• Mitochondria and Mood Disorders
• Benefits of photobiomodulation
• PBM Seminar at Gustave Roussy