Understanding the biphasic curve in photobiomodulation

When "more" doesn't mean "better"

Photobiomodulation is based on the idea that light stimulates cells. But be careful: too much light can have the opposite effect. This is known as the biphasic curve.

What is a biphasic curve?

It is a two-step process:

• At low doses, light stimulates the cell.
• At high doses, it slows down or blocks the effect.

This means you need to find the right intensity to achieve optimal results.

Why is this important?

This principle explains why a PBM protocol must be properly regulated:

• if the dose is too low, nothing happens;
• If it is too strong, the effect can be counterproductive.

By following the biphasic curve, we maximize the effects on:
✅ pain, ✅ healing, ✅ cell regeneration.

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Dosimetry Calculation