Publications & Research on Photobiomodulation
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Published on
September 14, 2019
September 14, 2019
Central Neurology and Cognition
Salehpour F. et al. - Transcranial photobiomodulation and cognitive performance in healthy young adults: a meta-analysis
A systematic review and meta-analysis evaluating the effect of transcranial photobiomodulation on cognition.

Published on
January 1, 2019
January 1, 2019
Psychiatry and Mental Health
Caldieraro, M.A., and Cassano, P. - Transcranial and Systemic Photobiomodulation in Major Depression: A Systematic Review
A systematic review of 17 clinical and preclinical studies on photobiomodulation in major depression. The authors report satisfactory tolerability but note that the evidence for efficacy is still preliminary.

Published on
July 1, 2018
July 1, 2018
Oncology and supportive care
Bensadoun RJ - Photobiomodulation, mucositis, radiation-induced dermatitis, and lymphedema in oncology: a narrative review
A 2018 narrative review on photobiomodulation in supportive oncology. The author describes a large body of data on oral mucositis and identifies radiation-induced dermatitis and lymphedema as indications worth exploring.

Published on
February 21, 2018
February 21, 2018
Oncology and supportive care
Hamblin MR et al. - Photobiomodulation and Cancer: What the Data Say—A Critical Review
A brief review from 2018 on the use of photobiomodulation in people with cancer. The authors report conflicting findings from animal studies, cite two clinical trials, and conclude that the topic requires further study.

Published on
January 19, 2018
January 19, 2018
Fundamentals and Mechanisms
Hamblin, M.R. - Photobiomodulation and Mitochondrial Redox Signaling: A Review of Mechanisms
A 2018 review focused on the mechanisms of photobiomodulation. It places mitochondria and cytochrome c oxidase at the center of the model, involving redox signaling, without measuring clinical efficacy.

Published on
May 19, 2017
May 19, 2017
Pain and inflammation
Hamblin, M.R. - Photobiomodulation and Anti-Inflammatory Effects: A Review of the Mechanisms
A review of the anti-inflammatory mechanisms of photobiomodulation, not a clinical trial. It identifies cytochrome c oxidase and calcium channels as the primary chromophores and describes a biphasic dose-response relationship.

Published on
October 1, 2016
October 1, 2016
Central Neurology and Cognition
Hamblin, M.R. - Transcranial Photobiomodulation for Brain Disorders: A Literature Review
A literature review, without a meta-analysis, focusing on transcranial photobiomodulation. The author classifies brain disorders into three groups and reviews the existing research, without providing any numerical data or conclusions regarding efficacy.

Published on
January 1, 2016
January 1, 2016
Fundamentals and Mechanisms
by Freitas LF et al. - Photobiomodulation and Proposed Mechanisms of Action: A Review of Mechanisms
A seminal review of proposed mechanisms of photobiomodulation. It describes cytochrome c oxidase as the primary chromophore, the dissociation of nitric oxide as the leading hypothesis, and the signaling pathways subsequently activated.

Published on
April 1, 2015
April 1, 2015
Fundamentals and Mechanisms
Anders J.J. et al. - Photobiomodulation: Adoption of a Unified Term: An Editorial on Nomenclature
A two-page editorial published in 2015: its authors note the shift from the term “low-level laser therapy” to “photobiomodulation.” This is not a study, and PubMed does not provide an abstract for it.
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